Neurological and Neurodegenerative disorders are complex to treat. Innovations in cell and gene therapies (CGTs) are creating new hope to the neurological patients and the CGT therapies deliver effective treatment by targeting the underlying molecular and cellular basis of neurodegenerative diseases such as Parkinson's, Alzheimer's, ALS, and spinal muscular atrophy, these approaches are expected to restore neural function and mitigate disease progression, and potentially even reverse the disease process.