This session at Cell & Gene Therapy World Conference 2025 will focus on the latest advancements in gene-editing technologies, including CRISPR-Cas9 and next-generation techniques like base and prime editing. Experts will discuss how these innovations improve precision and efficiency in genetic modification and offer new therapeutic possibilities. The session will also address ethical concerns, particularly around germline editing, and explore the regulatory challenges these technologies face as they move toward broader medical applications and beyond.