This session will address the ethical dilemmas surrounding gene-editing technologies like CRISPR on human germline cells. As these innovations offer the potential to prevent genetic disorders, the session will explore concerns about altering the human genome for future generations and the associated risks. Attendees of the Cell & Gene Therapy World Conference 2025 will discuss informed consent, social justice, and the possibility of creating genetic inequalities while considering the regulatory landscape that governs germline editing worldwide.