Clinical translation of regenerative medicine represents the definitive bridge between scientific discovery and patient impact. Despite significant progress in stem cell biology, regenerative medicine, and gene-modified therapies, the road to clinical application is laden with challenges, including regulatory hurdles, scalability of manufacturing, long-term safety and efficacy, and reimbursement. At our Cell & Gene Therapy event, the discussion will provide a perspective into how scientific innovation, evidence-informed evaluation, and collaborative multi-disciplinary science can propel the safe and effective implementation of regenerative medicine into mainstream clinical practice.